Acetyl Hexapeptide-8

Summary:Specification and formulation walkthrough for Acetyl Hexapeptide-8 (CAS 616204-22-9, MW 889.01): aqueous dissolution demonstration, typical raw-material specification parameters (Purity ≥98.0%, Water ≤7.0%, Acetate ≤15.0%, Solubility ≥5 mg/mL in H2O), recommended formulation range (100–1,000 ppm, pH 3–8), and 56-day topical test solution study on 17 women.

Verbatim Audio / Visual Transcript:Meet Acetyl Hexapeptide-8, a cosmetic peptide for fine-line care. This water-soluble ingredient is designed for topical skincare formulas. Specification summary: INCI Acetyl Hexapeptide-8, CAS No. 616204-22-9, Appearance white to off-white powder, Mass spec MW 889.01, Purity ≥98.0%, Water ≤7.0%, Acetate ≤15.0%, Solubility ≥5 mg/ml (H2O), Pack size 1–500g, Storage cool and dry (-5 to 8 °C), Shelf life 2 years. The supplier suggests 100 to 1,000 parts per million, with a formulation pH between 3 and 8. In one supplier-recorded study, 17 women used a 0.05% test solution twice daily for 56 days. By day 56, measured facial line volume was 21.92% lower, and line area was 21.51% lower than baseline. Explore Acetyl Hexapeptide-8 for skincare designed to improve the appearance of fine lines. For cosmetic formulation development.

Editorial & Verification Scope Note:Note: In the first 2 seconds of the video, the automated voiceover/caption mispronounces "Acetyl Hexapeptide-8" as "Axonyl Hexapeptide-8"; the on-screen specification table at 00:06 correctly lists INCI: Acetyl Hexapeptide-8 (CAS 616204-22-9). Study figures reflect supplier-reported topical test solution data (0.05%, n = 17) for cosmetic formulation development only.

Summary:Technical briefing on AHPX+, a cosmetic delivery system pairing Acetyl Hexapeptide-8 with a hydrolyzed chitosan carrier to enhance transdermal uptake. Reviews preclinical mouse-skin fluorescence penetration (+82% at 2 h, +219% at 8 h vs peptide alone) and a 28-day split-face study on 33 adults using a 1% AHPX+ cream (-30.4% crow’s-feet length, +17.6% R2 elasticity vs baseline).

Verbatim Audio / Visual Transcript:Meet AHPX+, a cosmetic ingredient system built around Acetyl Hexapeptide-8. Computational screening helped guide peptide selection. The selected peptide is paired with a hydrolyzed chitosan carrier. In a mouse skin model, the carrier formula showed higher relative fluorescence than the peptide alone at 2 and 8 hours (+82% at 2 h and +219% at 8 h vs peptide alone; supplier-reported preclinical data). Laboratory assays also explored the peptide’s molecular interactions. The supplier then conducted a 28-day half-face study with 33 adults comparing a cream containing 1% AHPX+ with a comparator cream. At day 28, measured crow’s-feet length fell 30.4%, while the R2 elasticity parameter rose 17.6% from baseline on the AHPX+ side. Explore AHPX+ for skincare designed to improve the appearance of fine lines and firmness. For cosmetic formulation development.

Editorial & Verification Scope Note:Preclinical fluorescence penetration and 28-day split-face figures reflect supplier-reported data for the tested 1% AHPX+ carrier formulation (n = 33). Confirm whether your inquiry requires neat Acetyl Hexapeptide-8 powder (CAS 616204-22-9) or a carrier/compound formulation system when requesting specifications and samples.